Starting from the late antique period, the buildings began to undergo transformations, readaptations and structural variations from time to time useful to meet the needs of the people passing through the area. Within the ancient walls, buildings constructed on top of the pre-existing ancient structures were born and renewed, until they became new historical testimony in their own right. Buildings, architectural and decorative elements are systematically demolished to repurpose building material. Houses are built with dissimilar stone elements, recycled and put in place according to logics capable of reinventing unusual harmonies as in the Casa della Colonna, a peasant house that is spread over two floors in which ancient materials are relocated. On the main façade, a large external staircase leads to the rooms on the upper floor which is accessed through a balcony; the nearby room is set on a vaulted structure supported by a reused column. Seemingly unusual architectural solutions that have nevertheless been functional to Sepino’s many lives.